Alexandria Bobe » Personnel



Alexandria Bobe

Graduate Student
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Biographical Info

The current goal of my project is to investigate the etiology of insulin-dependent Type 1 Diabetes (T1D) in germ-free (GF) IL10 knock-out mice.  We hypothesize the presence of intestinal microbiota plays a protective role against T1D in IL10KO mice and may shift diabetic outcome when introduced to GF-IL10KO mice at a specific age.  We aim to define autoimmune regulation in the absence of microbial stimuli and whether introduction of a particular microflora prevents or ameliorates T1D.

Categories: Graduate Students